منابع مشابه
Community participation in HIV cure research: perspectives from Thailand
Thailand aims to end its AIDS epidemic by 2030, and key strategies to effect this include an increase in HIV testing coverage to 90% for key populations (i.e. men who have sex with men, sex workers, people who inject drugs and partners of people living with HIV) and antiretroviral treatment (ART) initiation for all, regardless of CD4 cell count. In order to recruit more key populations into HIV...
متن کاملTowards an HIV cure
Given the challenge of delivering complex, expensive and potentially harmful antiretroviral therapy (ART) on a global level, there is intense interest in the development of short-term, well-tolerated regimens that allow individuals to interrupt therapy indefinitely without experiencing a rebound in viremia. This so-called "cure" or "remission" might be due to complete eradication of all replica...
متن کاملEradication and Cure of HIV
with nonprogressive HIV, typically where immune responses maintain virus replication at low or undetectable levels. There are several approaches currently in clinical trials studying aspects of cure of HIV. These can be broadly categorized as bone marrow transplant approaches, early cART therapy approaches, antilatency drug therapy approaches, immune manipulation approaches and gene therapy app...
متن کاملControversies in HIV cure research
BACKGROUND Antiretroviral therapy significantly reduces HIV viral burden and prolongs life, but does not cure HIV infection. The major scientific barrier to a cure is thought to be the persistence of the virus in cellular and/or anatomical reservoirs. DISCUSSION Most efforts to date, including pharmaco, immuno or gene therapy, have failed to cure patients, with the notable exception of a stem...
متن کاملCombined approaches for HIV cure.
PURPOSE OF REVIEW A serious effort has begun to develop therapies that may be capable of eradicating established HIV infection in man. Because of the biological complexity of HIV infection that persists despite potent antiretroviral therapy, it is widely believed that if such therapies can be developed they will involve complex, multimodality approaches. We highlight some of the recent studies ...
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ژورنال
عنوان ژورنال: Journal of Virus Eradication
سال: 2019
ISSN: 2055-6640
DOI: 10.1016/s2055-6640(20)31071-2